Determination of absolute stereochemistry for regulatory submission
نویسندگان
چکیده
منابع مشابه
Absolute Stereochemistry of the Diepoxins
The exciton coupled CD method has been applied to determine the absolute configuration of the diepoxins, spiroketaI-linked naphthodiepoxydecaIinones of fungal origin. The CD spectra of the bis-dimethylaminobenzoate derivatives of the diepoxins 71, land ~c, reveal a positive chiral twist between the two substituted hydroxyl groups and thus infer the $ configuration at both of these stereogenic c...
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Absolute stereochemistry of oils and viscous liquids can be difficult to determine. Co-crystallization involves generating a crystalline material consisting of more than one neutral compound. The combination of co-crystallization with both X-ray diffraction and chiral HPLC was particularly powerful in overcoming these difficulties for a series of chiral 3-arylbutanoic acids. Co-crystallization ...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2007
ISSN: 0108-7673
DOI: 10.1107/s0108767307093506